MLK-IN-1,99.06%
产品编号:Bellancom-111351| CAS NO:1627729-62-7| 分子式:C23H20N4O3S| 分子量:432.49
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MLK-IN-1
产品介绍 | MLK-IN-1 是一种强效的脑渗透特异性 MLK-3 抑制剂,从专利 US20140256733A1 中获得的化合物 68。 | ||||||||||||||||
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生物活性 | MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1. | ||||||||||||||||
体外研究 |
MLK-IN-1 (100 nM; pre-treatment 20 mins HIV-1 Tat) promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 | |||||||||||||||||
体内研究 | |||||||||||||||||
性状 | Solid | ||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 62.5 mg/mL (144.51 mM; ultrasonic and warming and heat to 80°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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参考文献 |