LY3372689|cas:2241514-56-5|西域试剂

LY3372689,98.74%

产品编号：Bellancom-144681| CAS NO：2241514-56-5| 分子式：C₁₆H₂₂FN₅O₃S| 分子量：383.44

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货号	价格	库存与货期
Bellancom-144681	￥3900.00	杭州北京（现货）
Bellancom-144681	￥6250.00	杭州北京（现货）
Bellancom-144681	￥12500.00	杭州北京（现货）

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LY3372689

产品介绍

LY3372689 (Formulaic Ia) 是一种具有口服活性的 O-GlcNAcase (OGA) 酶抑制剂。LY3372689 可用于 tau 蛋白病研究，包括阿尔茨海默病。

生物活性

LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor. LY3372689 can be used for tauopathies research, including Alzheimer’s disease.

体外研究

体内研究

LY3372689 shows a dose-dependent change in OGA enzyme occu-pancy (EO) following a single oral dose with a maximum EO of greater than 90% in rat.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

LY3372689 shows a dose-dependent change in OGA enzyme occu-pancy (EO) following a single oral dose with a maximum EO of greater than 90% in rat.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 250 mg/mL (651.99 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.6080 mL	13.0399 mL	26.0797 mL
5 mM	0.5216 mL	2.6080 mL	5.2159 mL
10 mM	0.2608 mL	1.3040 mL	2.6080 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式