Substance P(1-7) TFA|cas:2828433-22-1|西域试剂

Substance P(1-7) TFA,99.86%

产品编号：Bellancom-P1485A| CAS NO：2828433-22-1| 分子式：C₄₃H₆₆F₃N₁₃O₁₂| 分子量：1014.06

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货号	价格	库存与货期
Bellancom-P1485A	￥1100.00	杭州北京（现货）
Bellancom-P1485A	￥1800.00	杭州北京（现货）
Bellancom-P1485A	￥3900.00	杭州北京（现货）

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Substance P(1-7) TFA

产品介绍

Substance P(1-7) TFA 是神经肽 P 物质 (SP) 的片段。Substance P(1-7) TFA 可对孤束核产生抑制和缓和作用。

生物活性

Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) TFA gives depressor and bradycardic effects when applied to the nucleus tractus solitarius.

体外研究

体内研究

Substance P(1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P(1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P(1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

H₂O : 50 mg/mL (49.31 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.9861 mL	4.9307 mL	9.8613 mL
5 mM	0.1972 mL	0.9861 mL	1.9723 mL
10 mM	0.0986 mL	0.4931 mL	0.9861 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶