BMT-090605 hydrochloride,99.09%
产品编号：Bellancom-101290A| CAS NO：2231664-45-0| 分子式：C21H25ClN4O2| 分子量：400.90
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BMT-090605 hydrochloride
| 产品介绍 | BMT-090605 hydrochloride 是一种有效的选择性连接蛋白-2 相关激酶 1 (AAK1) 抑制剂，IC50 值为 0.6 nM。BMT-090605 hydrochloride 显示抗伤害活性。BMT-090605 hydrochloride 抑制 BMP-2 诱导蛋白激酶 (BIKE) 和细胞周期蛋白 G 相关激酶 GAK，IC50 值分别为 45 nM 和 60 nM。BMT-090605 hydrochloride 可用于神经性疼痛的研究。 | ||||||||||||
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| 生物活性 | BMT-090605 hydrochloride is a potent, selective the adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 value of 0.6 nM. BMT-090605 hydrochloride shows antinociceptive activity. BMT-090605 hydrochloride inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50 values of 45 nM and 60 nM, respectively. BMT-090605 hydrochloride can be used for the research of neuropathic pain. | ||||||||||||
| 体外研究 |
BMT-090605 hydrochloride shows AAK1inhibitory activity with an IC50 of 0.63 nM. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
| 体内研究 |
BMT-090605 hydrochloride(intrathecal; 0.3-3 µg/rat) causes antinociception by inhibiting AAK1 in the spinal cord. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究 |
BMT-090605 hydrochloride(intrathecal; 0.3-3 µg/rat) causes antinociception by inhibiting AAK1 in the spinal cord. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 性状 | Solid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| 参考文献 |
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