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Quinelorane dihydrochloride LY163502,99.0%

产品编号:Bellancom-103429| CAS NO:97548-97-5| 分子式:C14H24Cl2N4| 分子量:319.27

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-103429
5900.00 杭州 北京(现货)

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Quinelorane dihydrochloride LY163502

产品介绍 Quinelorane dihydrochloride (LY163502) 是一种有效的多巴胺 D3/D2 受体激动剂。 Quinelorane 具有用于神经和精神疾病研究的潜力。
生物活性

Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research.

体外研究
体内研究

Quinelorane dihydrochloride (LY163502; 0.003, 0.01 mg/kg; s.c.) reduces GABA efflux, with significant effects with 0.01 but not 0.003 mg/kg in male Wistar rats (300 g).
Quinelorane dihydrochloride (0.032, 0.32, 3.2, 5.6 mg/kg; IP) significantly and dose-dependently increases locomotor activity in the Sprague Dawley rats. There was no main effect of sex and sex interaction.
Quinelorane dihydrochloride significantly decreases activity in the male and female inbred FVB/NJ, BALB/cJ, BALB/cByJ, C57BL/6J, Swiss Webster, A/J, DBA/2J, 129S1/SvImJ, and 129S6/SvEvTac mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Quinelorane dihydrochloride (LY163502; 0.003, 0.01 mg/kg; s.c.) reduces GABA efflux, with significant effects with 0.01 but not 0.003 mg/kg in male Wistar rats (300 g).
Quinelorane dihydrochloride (0.032, 0.32, 3.2, 5.6 mg/kg; IP) significantly and dose-dependently increases locomotor activity in the Sprague Dawley rats. There was no main effect of sex and sex interaction.
Quinelorane dihydrochloride significantly decreases activity in the male and female inbred FVB/NJ, BALB/cJ, BALB/cByJ, C57BL/6J, Swiss Webster, A/J, DBA/2J, 129S1/SvImJ, and 129S6/SvEvTac mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状Solid
溶解性数据
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

参考文献

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