L-AP4 monohydrate L-APB monohydrate,99.0%
产品编号：Bellancom-100781B| CAS NO：2247534-79-6| 分子式：C4H12NO6P| 分子量：201.11
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，
L-AP4 monohydrate L-APB monohydrate
| 产品介绍 | L-AP4 (L-APB) monohydrate是一种有效的、代谢型谷氨酸受体 (mGluR) 的特异性激动剂，其对 mGlu4, mGlu8, mGlu6 和 mGlu7 受体的 EC50 值分别为 0.13, 0.29, 1.0, 249 μM。 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 生物活性 | L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively. | ||||||||
| 体外研究 | |||||||||
| 体内研究 |
L-AP4 (5-30 μg, intrathecal inhection 4-5 days) significantly increases the paw withdrawal threshold in response to application of von Frey filaments in eight nerve-ligated rats in a dose-dependent manner. Intrathecal administration of different doses of L-AP4 is not associated with any evident motor dysfunction. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
| ||||||||
| 体内研究 |
L-AP4 (5-30 μg, intrathecal inhection 4-5 days) significantly increases the paw withdrawal threshold in response to application of von Frey filaments in eight nerve-ligated rats in a dose-dependent manner. Intrathecal administration of different doses of L-AP4 is not associated with any evident motor dysfunction. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
| ||||||||
| 性状 | Solid | ||||||||
| 溶解性数据 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
| 储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) | ||||||||
| 参考文献 |
|
浙公网安备 33010802013016号