Gluten Exorphin C|cas:142479-62-7|西域试剂

Gluten Exorphin C,98.97%

产品编号：Bellancom-P1596| CAS NO：142479-62-7| 分子式：C₂₉H₄₅N₅O₈| 分子量：591.70

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货号	价格	库存与货期
Bellancom-P1596	￥500.00	杭州北京（现货）
Bellancom-P1596	￥1200.00	杭州北京（现货）
Bellancom-P1596	￥1800.00	杭州北京（现货）

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Gluten Exorphin C

产品介绍

Gluten exorphin C 是一种源自谷朊粉的阿片肽。在 GPI 和 MVD 检测中，抑制 μ opioid 和 δ opioid 活性，IC₅₀ 值分别为 40 μM 和13.5 μM。

生物活性

Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC₅₀ values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

体外研究

Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC₅₀s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

H₂O : 100 mg/mL (169.00 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.6900 mL	8.4502 mL	16.9005 mL
5 mM	0.3380 mL	1.6900 mL	3.3801 mL
10 mM	0.1690 mL	0.8450 mL	1.6900 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶