ERB-196 WAY-202196|cas:550997-55-2|西域试剂

ERB-196 WAY-202196,99.89%

产品编号：Bellancom-19468| CAS NO：550997-55-2| 分子式：C₁₇H₁₀FNO₂| 分子量：279.27

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-19468		￥5000.00	杭州北京（现货）
Bellancom-19468		￥8500.00	杭州北京（现货）

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ERB-196 WAY-202196

产品介绍

ERB-196 是一个非类固醇选择性雌激素受体-β (ERβ) 激动剂。

生物活性

ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist.

体外研究

体内研究

ERB-196 is a nonsteroidal selective estrogen receptor-β (ERβ) agonist. ERB-196 significantly reduces histopathologic evidence of injury to the gastrointestinal mucosal surface (0.7±0.1 vs. 2.3±0.2 for control; p<0.05). The mucosal mass of 10-cm segments of small bowel mucosa shows better preservation of mucosal mass than control treatment (63±20 [ERB-196] vs. 31±24 [control]), but this difference fails to reach statistical significance (p<0.06). The administration of ERB-196 is highly effective in the prevention of lethality. Consistent with the neutropenic rat model, ERB-196 significantly increases survival when compare with vehicle control.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

Ethanol : 16 mg/mL (57.29 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.5808 mL	17.9038 mL	35.8076 mL
5 mM	0.7162 mL	3.5808 mL	7.1615 mL
10 mM	0.3581 mL	1.7904 mL	3.5808 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献