Naxagolide (+-PHNO; Dopazinol)|cas:88058-88-2|西域试剂

Naxagolide (+-PHNO; Dopazinol),99.81%

产品编号：Bellancom-108237| CAS NO：88058-88-2| 分子式：C₁₅H₂₁NO₂| 分子量：247.33

纳沙戈利特((+)-PHNO；多巴胺)是一种有效的多巴胺D2(多巴胺受体)激动剂。纳沙戈利具有研究帕金森病(PD)的潜力。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-108237	￥3000.00	杭州北京（现货）
Bellancom-108237	￥4500.00	杭州北京（现货）
Bellancom-108237	￥9500.00	杭州北京（现货）
Bellancom-108237	￥15000.00	杭州北京（现货）

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Naxagolide (+-PHNO; Dopazinol)

产品介绍

Naxagolide ((+)-PHNO; Dopazinol) 是一种有效的多巴胺 D2 (dopamine D2) (Dopamine Receptor) 激动剂。Naxagolide 具有用于帕金森病 (PD) 研究的潜力。

生物活性

Naxagolide ((+)-PHNO; Dopazinol) is a potent dopamine D2 (Dopamine Receptor) agonist. Naxagolide has the potential for the research of parkinson's disease (PD).

体外研究

In vitro, Naxagolide ((+)-PHNO) inhibits binding of [³H]apomorphine (IC₅₀ = 23 nM) or [³H]spiperone (IC₅₀ = 55 nM) to rat striatal membranes.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

In mice, Naxagolide ((+)-PHNO) produces hypothermia (13 μg/kg i.p.) and postural asymmetry in the unilaterally caudectomized animal (4 μg/kg i.p.).
In the rat, Naxagolide ((+)-PHNO) produces stereotypy (10 μg/kg i.p.) and contralateral turning in 6-hydroxydopamine-lesioned animals (5 μg/kg i.p.) that lasted 1 to 3 hr.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 200 mg/mL (808.64 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.0432 mL	20.2159 mL	40.4318 mL
5 mM	0.8086 mL	4.0432 mL	8.0864 mL
10 mM	0.4043 mL	2.0216 mL	4.0432 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式