Exendin (5-39),99.81%
产品编号:Bellancom-P2497| CAS NO:196109-27-0| 分子式:C169H262N44O54S| 分子量:3806.30
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用,
Exendin (5-39)
产品介绍 | Exendin (5-39) 是一种强效的胰高血糖素样肽 1 (GLP-1 receptor) 受体拮抗剂。Exendin (5-39) 改善 β-淀粉样蛋白沉积的大鼠的记忆障碍。 | ||||||||
---|---|---|---|---|---|---|---|---|---|
生物活性 | Exendin (5-39) is a potent glucagon-like peptide 1 (GLP-1) receptor antagonist. Exendin (5-39) improves memory impairment in β-amyloid protein-treated rats. | ||||||||
体外研究 | |||||||||
体内研究 |
Exendin (5-39) (intracerebroventricular injection; 0.3 μg; once daily; 1-week) increases GLT-1 protein levels in the hippocampus of male Wistar rats. Additionally, hippocampal slices are prepared from Ex-treated or vehicle rats,Exendin (5-39) decreases fEPSP decay time and increases the input-output relation and decreased the paired-pulse ratio in the dentate gyrus (DG). Furthermore, Ex inhibits long-term depression but not long-term potentiation in the DG. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
| ||||||||
体内研究 |
Exendin (5-39) (intracerebroventricular injection; 0.3 μg; once daily; 1-week) increases GLT-1 protein levels in the hippocampus of male Wistar rats. Additionally, hippocampal slices are prepared from Ex-treated or vehicle rats,Exendin (5-39) decreases fEPSP decay time and increases the input-output relation and decreased the paired-pulse ratio in the dentate gyrus (DG). Furthermore, Ex inhibits long-term depression but not long-term potentiation in the DG. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
| ||||||||
性状 | Solid | ||||||||
溶解性数据 | |||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 |
Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) | ||||||||
参考文献 |