EN40
产品编号：Bellancom-122577| CAS NO：2094547-67-6| 分子式：C13H15NO2| 分子量：217.26
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EN40
| 产品介绍 | EN40 是一种有效的选择性乙醛脱氢酶 3A1 (ALDH3A1) 抑制剂，一种共价配体，IC50 值为 2 uM。 | ||||||||||||||||
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| 生物活性 | EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM | ||||||||||||||||
| 体外研究 |
EN40 (10-1000 μM; 48 hours) shows inhibitory effecton ALDH3A1 activity and impairs A549 cell survival. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay
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| 体内研究 (In Vivo) |
EN40 (intraperitoneal injection; 50mg/kg; from 14 days; once per day) exerts strong anti-tumorigenic effects in established A549 tumor xenografts, shows good tolerability with no body weight loss in mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究 |
EN40 (intraperitoneal injection; 50mg/kg; from 14 days; once per day) exerts strong anti-tumorigenic effects in established A549 tumor xenografts, shows good tolerability with no body weight loss in mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究 |
EN40 (intraperitoneal injection; 50mg/kg; from 14 days; once per day) exerts strong anti-tumorigenic effects in established A549 tumor xenografts, shows good tolerability with no body weight loss in mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 性状 | Oil | ||||||||||||||||
| 溶解性数据 |
In Vitro:
DMSO : 5 mg/mL (23.01 mM; Need ultrasonic) Ethanol : 2 mg/mL (9.21 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。 | ||||||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| 储存方式 |
4°C, stored under nitrogen *该产品在溶液状态不稳定，建议您现用现配，即刻使用。 | ||||||||||||||||
| 参考文献 |
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