SDZ 220-581 Ammonium salt|cas:179411-94-0|西域试剂

SDZ 220-581 Ammonium salt

产品编号：Bellancom-13059A| CAS NO：179411-94-0| 分子式：C₁₆H₂₀ClN₂O₅P| 分子量：386.77

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-13059A		￥1395.00	杭州北京（现货）
Bellancom-13059A		￥5952.00	杭州北京（现货）

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SDZ 220-581 Ammonium salt

产品介绍

SDZ 220-581 Ammonium salt 是一种口服生物利用度，有效的竞争性的 NMDA 受体拮抗剂，pK_i 值为 7.7。

生物活性

SDZ 220-581 Ammonium salt is an orally active, potent, competitive NMDA receptor antagonist with pK_i value of 7.7.

体外研究

体内研究

SDZ 220-581 (3.2-32 mg/kg; oral administration; for 24 hours; male OF-l mice) treatment dose-dependently protects mice against maximal electroshock seizures (MES). The time-course of protection by SDZ 220-581 is characterized by a rapid onset and long duration of action.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male OF-l mice (18-26 g)
Dosage:	3.2 mg/kg, 10 mg/kg, 32 mg/kg
Administration:	Oral administration; for 24 hours
Result:	Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male OF-l mice (18-26 g)
Dosage:	3.2 mg/kg, 10 mg/kg, 32 mg/kg
Administration:	Oral administration; for 24 hours
Result:	Dose-dependently protected mice against maximal electroshock seizures (MES) upon oral administration.