Calcitonin (human)|cas:21215-62-3|西域试剂

Calcitonin (human),96.06%

产品编号：Bellancom-P2273| CAS NO：21215-62-3| 分子式：C₁₅₁H₂₂₆N₄₀O₄₅S₃| 分子量：3417.87

降钙素是一种内源性降钙素受体降钙素激动剂人体降低全身血钙水平，抑制骨吸收。

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-P2273		￥2000.00	杭州北京（现货）
Bellancom-P2273		￥5500.00	杭州北京（现货）

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Calcitonin (human)

产品介绍

Calcitonin (human) 是一种降钙激素。Calcitonin 可降低血钙水平并抑制骨吸收，可用于高钙血症或骨质疏松症的研究。

生物活性

Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research.

体外研究

Calcitonin shows a potent inhibitory action on osteoclast mediated bone resorption.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Calcitonin (oral gavage; 2 mg/kg; once daily; 9 w) can inhibit cartilage degradation and prevent cartilage erosion.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female Sprague-Dawley rats
Dosage:	2 mg/kg
Administration:	Oral gavage; 2 mg/kg; once daily; 9 weeks
Result:	Suppressed ovariectomy-induced cartilage degradation (P<0.001) compared with the carrier control. Prevented cartilage erosion compared with treatment with the carrier alone (P<0.01), and the extent of erosions was comparable with that in sham-operated animals.

体内研究

Calcitonin (oral gavage; 2 mg/kg; once daily; 9 w) can inhibit cartilage degradation and prevent cartilage erosion.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female Sprague-Dawley rats
Dosage:	2 mg/kg
Administration:	Oral gavage; 2 mg/kg; once daily; 9 weeks
Result:	Suppressed ovariectomy-induced cartilage degradation (P<0.001) compared with the carrier control. Prevented cartilage erosion compared with treatment with the carrier alone (P<0.01), and the extent of erosions was comparable with that in sham-operated animals.

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

. Sexton PM, et al. Calcitonin. Current Medicinal Chemistry, 01 Nov 1999, 6(11):1067-1093. [Content Brief]

. Foster GV. Calcitonin. A review of experimental and clinical investigations. Postgrad Med J. 1968 May;44(511):411-22. [Content Brief]

. Bodil-Cecilie Sondergaard, et al. The effect of oral calcitonin on cartilage turnover and surface erosion in an ovariectomized rat model. Arthritis Rheum. 2007 Aug;56(8):2674-8. [Content Brief]

化学品安全说明书(MSDS)

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产品编号(Item Number)

批号(Lot Number)

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲)	S22-S24/25
危险品运输编码	NONH for all modes of transport
WGK德国	3

Calcitonin (human),96.06%

Calcitonin (human)

化学品安全说明书(MSDS)

质检证书(COA)

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