Fructosyl-lysine dihydrochloride Fructoselysine dihydrochloride|cas:96192-35-7|西域试剂

Fructosyl-lysine dihydrochloride Fructoselysine dihydrochloride,95.0%

产品编号：Bellancom-129380A| CAS NO：96192-35-7| 分子式：C₁₂H₂₆Cl₂N₂O₇| 分子量：381.25

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货号	价格	库存与货期
Bellancom-129380A	￥3200.00	杭州北京（现货）
Bellancom-129380A	￥5100.00	杭州北京（现货）
Bellancom-129380A	￥10000.00	杭州北京（现货）

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Fructosyl-lysine dihydrochloride Fructoselysine dihydrochloride

产品介绍

Fructosyl-lysine (Fructoselysine) dihydrochloride 是葡萄糖与赖氨酸通过美拉德反应生成的一种氨基糖基化产物 (amadori glycation)。Fructosyl-lysine 是葡萄糖烷的前体，葡萄糖烷是一种赖氨酸-精氨酸蛋白交联物，可作为糖尿病中检测的指标。

生物活性

Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride is the precursor to glucosepane, a lysine–arginine protein cross-link that can be an indicator in diabetes detection.

体外研究

Fructosyl-lysine dihydrochloride (5 mM; 0.5 hours) catalyzes the ATP-dependent conversion of [¹⁴C]fructoselysine to anionic products suggesting the existence of a fructoselysine-kinase activity in E .coli extracts.
Fructosyl-lysine dihydrochloride (100 μM; 1 hour) contains a carbohydrate moiety and appears to be phosphorylated, it can be converted to glucose 6-phosphate in bacterial extracts in E .coli extracts.
Fructosyl-lysine dihydrochloride (25 mM; 25 hours) lets E. coli growth at a rate of about one-third of that observed with glucose as a carbon source. Lysine itself does not support growth in the absence of other carbon source and does not affect the growth observed with glucose.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Fructosyl-lysine dihydrochloride and AGE residues is increased markedly in glomeruli, retina, sciatic nerve, and plasma protein in diabetic rats.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Fructosyl-lysine dihydrochloride and AGE residues is increased markedly in glomeruli, retina, sciatic nerve, and plasma protein in diabetic rats.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

H₂O : 40 mg/mL (104.92 mM; ultrasonic and warming and heat to 60°C)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.6230 mL	13.1148 mL	26.2295 mL
5 mM	0.5246 mL	2.6230 mL	5.2459 mL
10 mM	0.2623 mL	1.3115 mL	2.6230 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

参考文献