Apraglutide FE 203799|cas:1295353-98-8|西域试剂

Apraglutide FE 203799,99.37%

产品编号：Bellancom-P1714| CAS NO：1295353-98-8| 分子式：C₁₇₂H₂₆₃N₄₃O₅₂| 分子量：3765.25

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-P1714	￥1200.00	杭州北京（现货）
Bellancom-P1714	￥3300.00	杭州北京（现货）
Bellancom-P1714	￥5200.00	杭州北京（现货）
Bellancom-P1714	￥9800.00	杭州北京（现货）

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Apraglutide FE 203799

产品介绍

Apraglutide (FE 203799) 是一种合成的33-氨基酸肽和长效的 GLP-2类似物，能够增强全回肠切除的新生短肠综合征小猪的适应性和线性肠生长。

生物活性

Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum.

体外研究

体内研究

Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	NewbornDuroc piglets, 2–5 days old and weighing between 2-2.6 kg.
Dosage:	5 mg/kg/dose.
Administration:	Subcutaneously, twice on days 0 and 4 postsurgery.
Result:	On day 7, treated piglets were healthy, had significant lower fecal fat and energy losses and exhibited intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	NewbornDuroc piglets, 2–5 days old and weighing between 2-2.6 kg.
Dosage:	5 mg/kg/dose.
Administration:	Subcutaneously, twice on days 0 and 4 postsurgery.
Result:	On day 7, treated piglets were healthy, had significant lower fecal fat and energy losses and exhibited intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth.

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (26.56 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.2656 mL	1.3279 mL	2.6559 mL
5 mM	0.0531 mL	0.2656 mL	0.5312 mL
10 mM	0.0266 mL	0.1328 mL	0.2656 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture