(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)|cas:118102-98-0|西域试剂

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine),99.12%

产品编号：Bellancom-P2426| CAS NO：118102-98-0| 分子式：C₁₆₅H₂₅₁N₄₉O₄₀S₂| 分子量：3625.25

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货号	价格	库存与货期
Bellancom-P2426	￥2000.00	杭州北京（现货）
Bellancom-P2426	￥5000.00	杭州北京（现货）
Bellancom-P2426	￥8500.00	杭州北京（现货）

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(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)

产品介绍

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 是一种有效的竞争性甲状旁腺激素 (PTH) 拮抗剂，在牛肾皮质膜中的 K_i 值为 69 nM。(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 可用于生长发育调节。

生物活性

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a K_i of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation.

体外研究

(D-Trp12,Tyr34)-pTH (7-34) amide (0.05-10 μM) causes a concentration-dependent inhibition of PTHrP or PTH-stimulated cAMP formation in opossum kidney (OK) cells.
(D-Trp12,Tyr34)-pTH (7-34) amide (0.1-10 μM) attenuates inhibition of Nap_iT promoted by 1 nM of either PTHrP or PTH.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

(D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

H₂O : 25 mg/mL (6.90 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.2758 mL	1.3792 mL	2.7584 mL
5 mM	0.0552 mL	0.2758 mL	0.5517 mL
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture