Parathyroid hormone (1-34) (rat)|cas:98614-76-7|西域试剂

Parathyroid hormone (1-34) (rat)

产品编号：Bellancom-P2279| CAS NO：98614-76-7| 分子式：C₁₈₀H₂₉₁N₅₅O₄₈S₂| 分子量：4057.71

甲状旁腺激素（1-34）是甲状旁腺激素（PTH）受体激动剂，可增加大鼠血清PTH水平和骨量。

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-P2279		￥3200.00	杭州北京（现货）
Bellancom-P2279		￥9000.00	杭州北京（现货）

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Parathyroid hormone (1-34) (rat)

产品介绍

Parathyroid hormone (1-34) (rat) 是甲状旁腺激素。Parathyroid hormone (1-34) (rat) 可改善皮质和松质骨结构。Parathyroid hormone (1-34) (rat) 可用于骨质疏松症的研究。

生物活性

Parathyroid hormone (1-34) (rat) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis.

体外研究

体内研究

Parathyroid hormone (1-34) (rat) (s.c; 40 mg/kg; per day; for 4 weeks) promotes the formation of bone.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	ovariectomized (Ovx) rats
Dosage:	40 mg/kg
Administration:	s.c, per day, for 4 weeks
Result:	Preserved Cn-BV/TV and trabecular connectivity, and combined estrogen and PTH caused a 40% increment in Cn-BV/TV while maintaining comparable trabecular connectivity with that seen in the Shamoperated animals. Prevented further loss of connectivity and Cn-BV/TV, and combined estrogen and PTH resulted in as much as a 300% improvement in one of the parameters of trabecular connectivity, node to node strut length, and a 106% increase in Cn-BV/TV, with respect to the bone status at the initiation of treatment.

体内研究

Parathyroid hormone (1-34) (rat) (s.c; 40 mg/kg; per day; for 4 weeks) promotes the formation of bone.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	ovariectomized (Ovx) rats
Dosage:	40 mg/kg
Administration:	s.c, per day, for 4 weeks
Result:	Preserved Cn-BV/TV and trabecular connectivity, and combined estrogen and PTH caused a 40% increment in Cn-BV/TV while maintaining comparable trabecular connectivity with that seen in the Shamoperated animals. Prevented further loss of connectivity and Cn-BV/TV, and combined estrogen and PTH resulted in as much as a 300% improvement in one of the parameters of trabecular connectivity, node to node strut length, and a 106% increase in Cn-BV/TV, with respect to the bone status at the initiation of treatment.

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

参考文献

. V Shen, et al. Loss of cancellous bone mass and connectivity in ovariectomized rats can be restored by combined treatment with parathyroid hormone and estradiol. J Clin Invest. 1993 Jun;91(6):2479-87. [Content Brief]

. Yebin Jiang, et al. Recombinant human parathyroid hormone (1-34) [teriparatide] improves both cortical and cancellous bone structure. J Bone Miner Res. 2003 Nov;18(11):1932-41. [Content Brief]

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个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
WGK德国	3

Parathyroid hormone (1-34) (rat)

Parathyroid hormone (1-34) (rat)

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