GPR40 agonist 4|cas:2102196-57-4|西域试剂

GPR40 agonist 4,98.69%

产品编号：Bellancom-103083| CAS NO：2102196-57-4| 分子式：C₂₁H₁₇ClO₅S| 分子量：416.87

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-103083	￥1200.00	杭州北京（现货）
Bellancom-103083	￥1800.00	杭州北京（现货）
Bellancom-103083	￥3500.00	杭州北京（现货）
Bellancom-103083	￥5500.00	杭州北京（现货）
Bellancom-103083	￥7500.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

GPR40 agonist 4

产品介绍

GPR40 agonist 4 是一个强效的游离脂肪酸受体 1 (FFA1/GPR40) 激动剂，其 pEC₅₀ 值为 7.54。

生物活性

GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC₅₀ of 7.54.

体外研究

GPR40 agonist 4 tends to have a low risk of activating caspase-3/7.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Single oral administration of GPR40 agonist 4 (compound 20) robustly reduces the plasma glucose excursion and enhances insulin secretion during an oral glucose tolerance test (OGTT) in a dose-dependent manner from 1 to 10 mg/kg when GPR40 agonist 4 is dosed 60 min prior to the oral glucose challenge. The area under the curve of blood glucose (AUC_0-120min) and blood insulin (AUC_0-120min) reveal that the minimum effective dose of GPR40 agonist 4 is 3 mg/kg. The hyperglycemia state is also markedly improved in GPR40 agonist 4 (20 mg/kg) treated group.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 160 mg/mL (383.81 mM; Need ultrasonic and warming)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.3988 mL	11.9941 mL	23.9883 mL
5 mM	0.4798 mL	2.3988 mL	4.7977 mL
10 mM	0.2399 mL	1.1994 mL	2.3988 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式