Emixustat hydrochloride ACU-4429 hydrochloride,99.59%
产品编号：Bellancom-19720A| CAS NO：1141934-97-5| 分子式：C16H26ClNO2| 分子量：299.84
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Emixustat hydrochloride ACU-4429 hydrochloride
| 产品介绍 | Emixustat盐酸盐强抑制11-顺式-视黄醇的生产，IC50值为232±3 nM。 | ||||||||||||||||
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| 生物活性 | Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM. IC50 value: 232 nM Target: 11-cis-retinol Emixustat hydrochloride is a novel visual cycle modulator, in healthy volunteers. Oral Emixustat was safe and well tolerated when administered once daily for 14 days with minimal systemic adverse events reported. Evaluation of emixustat in subjects with geographic atrophy associated with dry age-related macular degeneration. | ||||||||||||||||
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| 性状 | Solid | ||||||||||||||||
| 溶解性数据 |
In Vitro:
DMSO : ≥ 44 mg/mL (146.74 mM) * "≥" means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 | ||||||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| 储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
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