2-Deoxy-D-glucose 6-phosphate disodium|cas:33068-19-8|西域试剂

2-Deoxy-D-glucose 6-phosphate disodium,98.0%

产品编号：Bellancom-139409A| CAS NO：33068-19-8| 分子式：C₆H₁₁Na₂O₈P| 分子量：288.10

2-脱氧-D-葡萄糖6-磷酸二钠是2-脱氧-D-葡萄糖的衍生物，通过己糖激酶对2-DG的作用在哺乳动物细胞中产生。2-脱氧-D-葡萄糖是一种葡萄糖类似物，作为葡萄糖代谢的竞争性抑制剂，通过对己糖激酶的作用抑制糖酵解。

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货号	价格	库存与货期
Bellancom-139409A	￥1500.00	杭州北京（现货）
Bellancom-139409A	￥2900.00	杭州北京（现货）
Bellancom-139409A	￥4600.00	杭州北京（现货）

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2-Deoxy-D-glucose 6-phosphate disodium

产品介绍

2-Deoxy-D-glucose 6-phosphate disodium 是 2-Deoxy-D-glucose 的衍生物，在哺乳动物细胞中由己糖激酶作用于 2-DG 产生。2-Deoxy-D-glucose 6-phosphate disodium 是葡萄糖代谢的竞争性抑制剂，通过对己糖激酶的作用抑制糖酵解。

生物活性

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase.

体外研究

体内研究

性状

Oil

溶解性数据

In Vitro:

H₂O : 250 mg/mL (867.75 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.4710 mL	17.3551 mL	34.7102 mL
5 mM	0.6942 mL	3.4710 mL	6.9420 mL
10 mM	0.3471 mL	1.7355 mL	3.4710 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30. [Content Brief]

. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234. [Content Brief]

化学品安全说明书(MSDS)

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质检证书(COA)

产品编号(Item Number)

批号(Lot Number)

危害码 (欧洲)	T: Toxic;
风险声明 (欧洲)	23/24/25-36/37/38
安全声明 (欧洲)	26-36/37/39-45

2-Deoxy-D-glucose 6-phosphate disodium,98.0%

2-Deoxy-D-glucose 6-phosphate disodium

化学品安全说明书(MSDS)

质检证书(COA)

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