MEISi-2,98.0%
产品编号：Bellancom-134259| CAS NO：2250156-71-7| 分子式：C18H14N2O3| 分子量：306.32
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MEISi-2
| 产品介绍 | MEISi-2 是一种选择性的 MEIS 抑制剂，MEIS 是造血干细胞 (HSC) 自我更新的关键调控因子。MEISi-2 被开发用于心脏损伤、造血问题、骨髓移植和癌症的研究。 | |||||||||
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| 生物活性 | MEISi-2 is a selective inhibitor of MEIS, a key regulator of hematopoietic stem cell (HSC) self-renewal. MEISi-2 is developed for the research of cardiac injuries, hematopoiesis issues, bone marrow transplantations, and cancer. | |||||||||
| 体外研究 |
MEISi-2 does not significantly inhibit the PBX-Luc-reporter. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
| 体内研究 |
MEISi-2 (10 µM; i.p.; at day 1, day 4 and day 7) functionally inhibits MEIS in vivo, thus they induces c-Kit+ cell, Sca1+ cell, CD150+ cell, LSK HSPCs, LSKCD34low HSC content and LSKCD150+CD48- HSC content. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究 |
MEISi-2 (10 µM; i.p.; at day 1, day 4 and day 7) functionally inhibits MEIS in vivo, thus they induces c-Kit+ cell, Sca1+ cell, CD150+ cell, LSK HSPCs, LSKCD34low HSC content and LSKCD150+CD48- HSC content. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 性状 | Solid | |||||||||
| 溶解性数据 |
In Vitro:
H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble) DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble) | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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| 参考文献 |
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