CO23|cas:1370363-74-8|西域试剂

CO23,98.01%

产品编号：Bellancom-130012| CAS NO：1370363-74-8| 分子式：C₁₉H₁₈I₂N₂O₄| 分子量：592.17

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-130012		￥8500.00	杭州北京（现货）
Bellancom-130012		￥14500.00	杭州北京（现货）

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CO23

产品介绍

CO23 是一种选择性的 TRα (甲状腺激素受体)激动剂，用于调节生长发育。CO23 能够通过血脑屏障转运。

生物活性

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier.

体外研究

体内研究

CO23 (ip; 0.04-5.0 nmol/g) has ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses are equally effective. CO23 has no effect at the lowest dose of 0.04 nmol/g and increases Dio1 mRNA 5-, 10-, and 15-fold at the doses of 0.8, 2.5, and 5 nmol/g, respectively.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Hypothyroid Wistar rats
Dosage:	0.04, 0.8, 2.5, and 5.0 nmol/g
Administration:	Ip
Result:	Had ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses were equally effective.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Hypothyroid Wistar rats
Dosage:	0.04, 0.8, 2.5, and 5.0 nmol/g
Administration:	Ip
Result:	Had ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses were equally effective.

性状

Solid

溶解性数据

In Vitro:

DMSO : 250 mg/mL (422.18 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.6887 mL	8.4435 mL	16.8870 mL
5 mM	0.3377 mL	1.6887 mL	3.3774 mL
10 mM	0.1689 mL	0.8444 mL	1.6887 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式