Fructosyl-lysine (Fructoselysine) is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine is the precursor to glucosepane, a lysine–arginine protein cross-link that can be an indicator in diabetes detection.

Fructosyl-lysine (5 mM; 0.5 hours) catalyzes the ATP-dependent conversion of [¹⁴C]fructoselysine to anionic products suggesting the existence of a fructoselysine-kinase activity in E .coli extracts.
Fructosyl-lysine (100 μM; 1 hour) contains a carbohydrate moiety and appears to be phosphorylated, it can be converted to glucose 6-phosphate in bacterial extracts in E .coli extracts.
Fructosyl-lysine (25 mM; 25 hours) lets E. coli growth at a rate of about one-third of that observed with glucose as a carbon source. Lysine itself does not support growth in the absence of other carbon source and does not affect the growth observed with glucose.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Fructosyl-lysine and AGE residues is increased markedly in glomeruli, retina, sciatic nerve, and plasma protein in diabetic rats.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Fructosyl-lysine and AGE residues is increased markedly in glomeruli, retina, sciatic nerve, and plasma protein in diabetic rats.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

• . Rabbani N, et al. Hidden complexities in the measurement of fructosyl-lysine and advanced glycation end products for risk prediction of vascular complications of diabetes. Diabetes. 2015 Jan;64(1):9-11.  [Content Brief]

  . Karachalias N, et al. Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochem Soc Trans. 2003 Dec;31(Pt 6):1423-5.  [Content Brief]