Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.

Stearoyl-L-carnitine (0.01-10 μM) inhibits glycine (30 μM) transports by 16.8% at concentrations up 3 μM in Xenopus laevis oocytes.
Stearoyl-L-carnitine (500 μM; 30 min) inhibits Na⁺-dependent [³H]carnitine (20 nM) uptake by ~50% in HPCT cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC).

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC).

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

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  . Carland JE, et, al. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. Br J Pharmacol. 2013 Feb;168(4):891-902.  [Content Brief]

  . Huang W, et, al. Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells. Biochem Pharmacol. 1999 Oct 15;58(8):1361-70.  [Content Brief]