Ganglioside GM3|cas:124579-05-1|西域试剂

Ganglioside GM3,95.51%

产品编号：Bellancom-114456| CAS NO：124579-05-1| 分子式：C₅₉H₁₀₈N₂O₂₁| 分子量：1181.49

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-114456		￥2800.00	杭州北京（现货）
Bellancom-114456		￥9800.00	杭州北京（现货）

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Ganglioside GM3

产品介绍

Ganglioside GM3 是 a、b 和 c 系列神经节苷的前体，与表皮生长因子和胰岛素受体等跨膜受体相互作用，通过创造专门的脂质环境调节受体功能。Ganglioside GM3 由 GM3 合成酶合成，可用于高胆固醇血症的研究。

生物活性

Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia.

体外研究

Ganglioside GM3, produced by addition of sialic acid to LacCer, is expressed mainly in adipose tissue and muscle in humans and mice, and liver and serum in humans. GM3 expression in adipocytes is induced by stimulation of the inflammatory cytokines TNF-α and IL-1β, derived from tissue macrophages.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

DMSO : 125 mg/mL (105.80 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.8464 mL	4.2319 mL	8.4639 mL
5 mM	0.1693 mL	0.8464 mL	1.6928 mL
10 mM	0.0846 mL	0.4232 mL	0.8464 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献