FASN-IN-4|cas:1375105-96-6|西域试剂

FASN-IN-4,99.21%

产品编号：Bellancom-12648| CAS NO：1375105-96-6| 分子式：C₂₆H₂₇N₃O₄S| 分子量：477.58

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-12648		￥1900.00	杭州北京（现货）

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FASN-IN-4

产品介绍

FASN-IN-4 是高效的脂肪酸合酶 FASN 抑制剂，IC₅₀ 值为 10 nM (WO2012064642A1, compound 29)。FASN-IN-4 还抑制 SARS-CoV-2，EC₅₀ 为 18.6 nM。

生物活性

FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC₅₀ of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 also inhibits SARS-CoV-2 with an EC₅₀ of 18.6 nM.

体外研究

The FASN inhibitor, FASN-IN-4 inhibits SARS-CoV-2 replication, and has the potential for COVID-19 research.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

. Nicholas D. Adams, et al. Fatty acid synthase inhibitors. WO2012064642A1.

. Junjun Chu, et al. Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nat Metab. 2021 Nov;3(11):1466-1475. [Content Brief]

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