(R)-3-Hydroxybutanoic acid-13C2 (sodium) (R-(-)-3-Hydroxybutanoic acid-13C2 (sodium); (R)-3-Hydroxybutyric acid-13C2 (sodium))|cas:202114-54-3|西域试剂

(R)-3-Hydroxybutanoic acid-¹³C₂ (sodium) (R-(-)-3-Hydroxybutanoic acid-¹³C₂ (sodium); (R)-3-Hydroxybutyric acid-¹³C₂ (sodium)),98.0%

产品编号：Bellancom-B0228S10| CAS NO：202114-54-3| 分子式：C₂¹³C₂H₇NaO₃| 分子量：128.07

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货号	价格	库存与货期
Bellancom-B0228S10	￥700.00	杭州北京（现货）
Bellancom-B0228S10	￥1400.00	杭州北京（现货）
Bellancom-B0228S10	￥2200.00	杭州北京（现货）

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(R)-3-Hydroxybutanoic acid-¹³C₂ (sodium) (R-(-)-3-Hydroxybutanoic acid-¹³C₂ (sodium); (R)-3-Hydroxybutyric acid-¹³C₂ (sodium))

产品介绍

(R)-3-Hydroxybutanoic acid-¹³C₂ (sodium) 是(R)-3-Hydroxybutanoic acid (sodium) (HY-W015851)的 ¹³C 标记物。(R)-3-Hydroxybutanoic acid (sodium) 是一种代谢物，由 3-羟基丁酸脱氢酶催化乙酸乙酯获得。(R)-3-Hydroxybutanoic acid sodium 可作为营养来源和维生素、抗生素和信息素的前体。

生物活性

(R)-3-Hydroxybutanoic acid-¹³C₂ (sodium) is the ¹³C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

H₂O : 125 mg/mL (976.03 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	7.8082 mL	39.0411 mL	78.0823 mL
5 mM	1.5616 mL	7.8082 mL	15.6165 mL
10 mM	0.7808 mL	3.9041 mL	7.8082 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

. Ide T. Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. Biosci Biotechnol Biochem. 2010;74(8):1578-82. [Content Brief]

. Mateusz Biernacki, et al. Production of (R)-3-hydroxybutyric acid by Arxula adeninivorans. AMB Express. 2017 Dec;7(1):4. [Content Brief]

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(R)-3-Hydroxybutanoic acid-13C2 (sodium) (R-(-)-3-Hydroxybutanoic acid-13C2 (sodium); (R)-3-Hydroxybutyric acid-13C2 (sodium)),98.0%