DPP-IV-IN-1|cas:625110-37-4|西域试剂

DPP-IV-IN-1,98.79%

产品编号：Bellancom-U00346| CAS NO：625110-37-4| 分子式：C₁₁H₁₈FN₃O₂| 分子量：243.28

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-U00346		￥17500.00	杭州北京（现货）
Bellancom-U00346		￥28000.00	杭州北京（现货）

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DPP-IV-IN-1

产品介绍

DPP-IV-IN-1 是一种有效的 dipeptidyl peptidase IV (DPP-IV) 抑制剂，IC₅₀ 值为 4.6 nM；DPP-IV 为一种特异性的丝氨酸蛋白酶 (serine protease)。

生物活性

DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC₅₀ of 4.6 nM.

体外研究

体内研究

DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading, and significantly suppresses hyperglycemia at the dose of 0.3 mg/kg in a rat model of obesity and impaired glucose tolerance. The effect is based on its inhibitory effect on plasma DPP-IV activity.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 125 mg/mL (513.81 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.1105 mL	20.5525 mL	41.1049 mL
5 mM	0.8221 mL	4.1105 mL	8.2210 mL
10 mM	0.4110 mL	2.0552 mL	4.1105 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式