IM176OUT05|cas:1643659-96-4|西域试剂

IM176OUT05,99.38%

产品编号：Bellancom-125283| CAS NO：1643659-96-4| 分子式：C₁₁H₁₈ClN₅| 分子量：255.75

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货号	价格	库存与货期
Bellancom-125283	￥2300.00	杭州北京（现货）
Bellancom-125283	￥3800.00	杭州北京（现货）
Bellancom-125283	￥7600.00	杭州北京（现货）
Bellancom-125283	￥12000.00	杭州北京（现货）

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IM176OUT05

产品介绍

IM176OUT05 是一种高溶解度的双胍。IM176OUT05 激活干细胞代谢，促进毛发再生，并在多能干细胞生成过程中增加干性诱导和维护。IM176OUT0 抑制线粒体电子传递链 (ETC) 活性，IC₅₀ 为 3.2 μM。

生物活性

IM176OUT05 is a high solubility biguanide. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC₅₀ of 3.2 μM.

体外研究

IM176OUT05 (0.1-10 μM；24 小时) 抑制线粒体功能，降低氧消耗率 (OCR) 以抑制线粒体电子传递链 (ETC) 活性，IC₅₀ 为 3.2 μM。
IM176OUT05 (10 μM；6 天) 改善小鼠和人诱导多能干细胞 (iPSCs) 的干细胞多能性的获取和维持。
IM176OUT05 (10 和 100 nM) 促进糖酵解代谢的转变，诱导糖酵解相关基因和 ETC 复合酶的表达。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

IM176OUT05 (200 μL, 1%；用于脱毛区域，每日一次) 通过刺激毛囊周期和增加毛囊数量，促进小鼠毛发再生。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	7-week-old C57BL/6 mice
Dosage:	200 μL, 1%
Administration:	Apply to the depilated area; 200 μL, 1%, once daily
Result:	Strongly promoted the hair regrowth, especially in female mice.

体内研究

IM176OUT05 (200 μL, 1%；用于脱毛区域，每日一次) 通过刺激毛囊周期和增加毛囊数量，促进小鼠毛发再生。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	7-week-old C57BL/6 mice
Dosage:	200 μL, 1%
Administration:	Apply to the depilated area; 200 μL, 1%, once daily
Result:	Strongly promoted the hair regrowth, especially in female mice.