inS3-54A18|cas:328998-53-4|西域试剂

inS3-54A18,99.53%

产品编号：Bellancom-103128| CAS NO：328998-53-4| 分子式：C₂₃H₁₆ClNO₂| 分子量：373.83

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-103128	￥1100.00	杭州北京（现货）
Bellancom-103128	￥1600.00	杭州北京（现货）
Bellancom-103128	￥2600.00	杭州北京（现货）
Bellancom-103128	￥9500.00	杭州北京（现货）
Bellancom-103128	￥16000.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

inS3-54A18

产品介绍

inS3-54A18 是有一种有效的 STAT3 抑制剂，具有抗癌作用。

生物活性

inS3-54A18 is a potent STAT3 inhibitor, with anti-cancer properties.

体外研究

inS3-54A18 (5 μM) reduces wound healing to 64% and 76% for A549 and MDA-MB-231 cells, respectively. inS3-54A18 at 10 μM further reduces the healing to 47% and 39%, respectively. inS3-54A18 inhibits the expression of STAT3 downstream target genes and the binding of STAT3 to its endogenous target sequences. inS3-54A18 does not affect the constitutive or IL-6-induced STAT3 activation (Tyr705 phosphorylation) but represses STAT3 target gene (survivin) expression.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

inS3-54A18 (200 mg/kg, p.o.) inhibits tumor growth, metastasis and expression of STAT3 target genes in a mouse xenograft model of A549 cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

inS3-54A18 (200 mg/kg, p.o.) inhibits tumor growth, metastasis and expression of STAT3 target genes in a mouse xenograft model of A549 cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (267.50 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.6750 mL	13.3751 mL	26.7501 mL
5 mM	0.5350 mL	2.6750 mL	5.3500 mL
10 mM	0.2675 mL	1.3375 mL	2.6750 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式