Hydrochlorothiazid-d2 HCTZ-d2,98.89%

产品编号:Bellancom-B0252S| CAS NO:1219798-89-6| 分子式:C7H6D2ClN3O4S2| 分子量:299.75

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-B0252S
800.00 杭州 北京(现货)
Bellancom-B0252S
2300.00 杭州 北京(现货)
Bellancom-B0252S
3900.00 杭州 北京(现货)

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Hydrochlorothiazid-d2 HCTZ-d2

产品介绍 Hydrochlorothiazid-d2 是 Hydrochlorothiazide 的氘代物。Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药,可抑制转化 TGF-β/Smad 信号通路。Hydrochlorothiazide 通过打开钙激活钾 (KCA) 通道具有直接的血管松弛作用。Hydrochlorothiazide 改善心脏功能,减少纤维化并具有降压作用。
生物活性

Hydrochlorothiazid-d2 is the deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
体内研究
性状Solid
溶解性数据
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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