28-Homobrassinolide 28-高芸苔素内脂|cas:82373-95-3|西域试剂

28-Homobrassinolide 28-高芸苔素内脂

产品编号：Bellancom-N9435| CAS NO：82373-95-3| 分子式：C₂₉H₅₀O₆| 分子量：494.70

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货号	价格	库存与货期
Bellancom-N9435	￥500.00	杭州北京（现货）
Bellancom-N9435	￥800.00	杭州北京（现货）
Bellancom-N9435	￥1600.00	杭州北京（现货）
Bellancom-N9435	￥2500.00	杭州北京（现货）
Bellancom-N9435	￥3900.00	杭州北京（现货）

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产品介绍

28-Homobrassinolide 是一种植物类固醇。28-Homobrassinolide 可用于胆固醇和葡萄糖体内平衡的研究。

生物活性

28-Homobrassinolide is a phytosteroid. 28-Homobrassinolide can be used for the research of cholesterol and glucose homeostasis.

体外研究

28-Homobrassinolide (5-20 μM) 表明 HepG2 细胞中的葡萄糖利用以及 ABCA1 和 SREBP2 蛋白表达增加了 2 倍。
28-Homobrassinolide 降低组织葡萄糖和胆固醇水平，增加胆固醇水平和组织己糖激酶活性。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay

Cell Line:	HepG2 cells
Concentration:	1 µM, 5 µM, 10 µM, 20 µM, 30 µM, 40 µM, and 80 µM
Incubation Time:	24 h
Result:	The IC₅₀ value of 40.57µM obtained by the MTT assay.

Western Blot Analysis

Cell Line:	HepG2 cells
Concentration:	5, 10, and 20 μM
Incubation Time:	12 h
Result:	Exhibited an increase in both ABCA1 and SREBP2 markers.

体内研究
(In Vivo)

28-HB（1-20 μg/天；持续 6 周）显示高脂肪饮食喂养的 C57BL/6 小鼠的主动脉脂肪沉积和血清标志物水平显着降低。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	High-fat diet-fed C57BL/6 mice
Dosage:	1-20 μg/day
Administration:	For 6 weeks
Result:	Observed a significant decrease in lipid deposition.

体内研究

28-HB（1-20 μg/天；持续 6 周）显示高脂肪饮食喂养的 C57BL/6 小鼠的主动脉脂肪沉积和血清标志物水平显着降低。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	High-fat diet-fed C57BL/6 mice
Dosage:	1-20 μg/day
Administration:	For 6 weeks
Result:	Observed a significant decrease in lipid deposition.

体内研究

28-HB（1-20 μg/天；持续 6 周）显示高脂肪饮食喂养的 C57BL/6 小鼠的主动脉脂肪沉积和血清标志物水平显着降低。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	High-fat diet-fed C57BL/6 mice
Dosage:	1-20 μg/day
Administration:	For 6 weeks
Result:	Observed a significant decrease in lipid deposition.

性状

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

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产品编号(Item Number)

批号(Lot Number)

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