Velsecorat AZD7594; AZ13189620|cas:1196509-60-0|西域试剂

Velsecorat AZD7594; AZ13189620,99.60%

产品编号：Bellancom-111453| CAS NO：1196509-60-0| 分子式：C₃₂H₃₂F₂N₄O₆| 分子量：606.62

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货号	价格	库存与货期
Bellancom-111453	￥1600.00	杭州北京（现货）
Bellancom-111453	￥2200.00	杭州北京（现货）
Bellancom-111453	￥4900.00	杭州北京（现货）
Bellancom-111453	￥7900.00	杭州北京（现货）
Bellancom-111453	￥12500.00	杭州北京（现货）

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Velsecorat AZD7594; AZ13189620

产品介绍

AZD7594 是一种有效的，选择性非甾体类糖皮质激素受体 (glucocorticoid receptor) 调节剂，IC₅₀ 值为 0.9 nM。

生物活性

AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC₅₀ of 0.9 nM.

体外研究

AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC₅₀ of 0.9 nM. AZD7594 shows no effect on progesterone receptor, mineralocorticoid receptor, Androgen receptor, ERα or ERβ (IC₅₀, > 10 μM).

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

AZD7594 has anti-inflammatory activity, and efficiently inhibits rat lung edema.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

AZD7594 has anti-inflammatory activity, and efficiently inhibits rat lung edema.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : ≥ 83.3 mg/mL (137.32 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.6485 mL	8.2424 mL	16.4848 mL
5 mM	0.3297 mL	1.6485 mL	3.2970 mL
10 mM	0.1648 mL	0.8242 mL	1.6485 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式