Polaprezinc 聚普瑞锌; Zinc L-carnosine,98.0%

产品编号:Bellancom-B0729| CAS NO:107667-60-7| 分子式:C9H11N4O3Zn| 分子量:288.59

Polaprezinc 是由锌、L-肌肽构成的口服螯合物,具有抗氧化、抗溃疡、抗炎活性。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用,

货号 包装 价格 库存与货期 购买量 操作
Bellancom-B0729
500.00 杭州 北京(现货)
Bellancom-B0729
1200.00 杭州 北京(现货)
Bellancom-B0729
1900.00 杭州 北京(现货)

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Polaprezinc 聚普瑞锌; Zinc L-carnosine

产品介绍 Polaprezinc 是由锌、L-肌肽构成的口服螯合物,具有抗氧化、抗溃疡、抗炎活性。
生物活性

Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities.

体外研究
体内研究

Polaprezinc (PZ) is an antiulcer drug and a chelating compound consisting of a zinc ion, L-carnosine, a β-alanine dipeptide and L-histidine. Polaprezinc exerts antioxidant effects and scavenges free radicals. The efficacy of Polaprezinc is reported for acute radiation proctitis in an animal model and demonstrates that Polaprezinc has an anti-inflammatory effect following exposure to radiation.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Polaprezinc (PZ) is an antiulcer drug and a chelating compound consisting of a zinc ion, L-carnosine, a β-alanine dipeptide and L-histidine. Polaprezinc exerts antioxidant effects and scavenges free radicals. The efficacy of Polaprezinc is reported for acute radiation proctitis in an animal model and demonstrates that Polaprezinc has an anti-inflammatory effect following exposure to radiation.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状Solid
溶解性数据
In Vitro: 

H2O : 3.37 mg/mL (11.68 mM; ultrasonic and warming and adjust pH to 1-2 with HCl)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.4651 mL 17.3256 mL 34.6512 mL
5 mM 0.6930 mL 3.4651 mL 6.9302 mL
10 mM 0.3465 mL 1.7326 mL 3.4651 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

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107667-60-7结构式

107667-60-7

文献:Angewandte Chemie - International Edition, , vol. 53, # 1 p. 193 - 198 Angew. Chem., , vol. 126, # 1 p. 197 - 202,6
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