Transglutaminase is an enzyme that forms crosslinks between protein molecules. Transglutaminase catalyses the formation of an isopeptide bond between the group of γ-carboxamides of glutamine residues and the first-order ε-amine groups of different compounds. Transglutaminase is involved in many physiological processes, including coagulation, antibacterial immune reactions and photosynthesis.

Transglutaminase activity can be increased by Co²⁺, Ba²⁺ and K⁺.
Microbial transglutaminases are inhibited by Zn²⁺, Cu²⁺, Hg²⁺ and Pb²⁺ ions which bind to the thiol group of cysteine in the active centre.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

• . Kieliszek M, Misiewicz A. Microbial transglutaminase and its application in the food industry. A review. Folia Microbiol (Praha). 2014 May;59(3):241-50.  [Content Brief]