Prezalumab AMG 557,95.00%
产品编号：Bellancom-P99414| CAS NO：1523164-68-2
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Prezalumab AMG 557
| 产品介绍 | Prezalumab (AMG 557) 是一种靶向 ICOSL 和 BAFF 的人源 IgG2 单克隆抗体。Prezalumab 对系统性红斑狼疮关节炎有研究作用。Prezalumab 可用于干燥综合征皮肤红斑狼疮、银屑病和系统性红斑狼疮 (SLE) 的研究。 | |||||||||||||||||||||
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| 生物活性 | Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE). | |||||||||||||||||||||
| 体外研究 | ||||||||||||||||||||||
| 体内研究 |
Prezalumab shows more efficacious effects than single ICOSL or BAFF inhibitor in mouse NZB/NZW lupus model and collagen induced arthritis (CIA) models. Prezalumab reduces B cell in cynomolgus monkeys, same as the pharmacological effect of BAFF inhibition.
西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||||||||||||||
| 体内研究 |
Prezalumab shows more efficacious effects than single ICOSL or BAFF inhibitor in mouse NZB/NZW lupus model and collagen induced arthritis (CIA) models. Prezalumab reduces B cell in cynomolgus monkeys, same as the pharmacological effect of BAFF inhibition.
西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||||||||||||||
| 性状 | Liquid | |||||||||||||||||||||
| 溶解性数据 | ||||||||||||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||||||||||||||
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. | |||||||||||||||||||||
| 参考文献 |
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