PGD2-IN-1,98.27%

产品编号:Bellancom-101430| CAS NO:885066-67-1| 分子式:C23H23Cl2N3O3| 分子量:460.35

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-101430
1800.00 杭州 北京(现货)
Bellancom-101430
2800.00 杭州 北京(现货)
Bellancom-101430
7500.00 杭州 北京(现货)
Bellancom-101430
12000.00 杭州 北京(现货)

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PGD2-IN-1

产品介绍 PGD2-IN-1 是 DP 受体拮抗剂, 来自专利 WO 2006044732 A2,化合物实例 15 (d),IC50 值为 0.3 nM。
生物活性

PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d); has an IC50 of 0.3 nM.

体外研究

Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
体内研究
性状Solid
溶解性数据
In Vitro: 

DMSO : ≥ 25 mg/mL (54.31 mM)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1723 mL 10.8613 mL 21.7226 mL
5 mM 0.4345 mL 2.1723 mL 4.3445 mL
10 mM 0.2172 mL 1.0861 mL 2.1723 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

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