Tesidolumab LFG316; Anti-Human C5 Recombinant Antibody
产品编号：Bellancom-P99322| CAS NO：1531594-08-7
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Tesidolumab LFG316; Anti-Human C5 Recombinant Antibody
| 产品介绍 | Tesidolumab (LFG316) 是一种全人IgG1/λ抗c5单克隆抗体，分子量为143 kDa(不含糖基化)。Tesidolumab (LFG316)阻断C5的切割，防止膜攻击复合体的后续形成。 |
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| 生物活性 | Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex. |
| 体外研究 |
Tesidolumab (LFG316) possesses a half-life in humans of approximately 9 days. Tesidolumab (LFG316) binds to a distinct epitope to that of eculizumab and ravulizumab, distant to Arg 885. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 | |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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