Vudalimab,99.90%
产品编号：Bellancom-P99166| CAS NO：2329669-72-7
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Vudalimab
| 产品介绍 | Vudalimab 是一种有效的 PD-1 和 CTLA-4 双重抑制剂，是一种完全人源化的双特异性单克隆抗体。Vudalimab 靶向免疫检查点受体 PD-1 和 CTLA-4，促进肿瘤选择性 T 细胞激活。 |
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| 生物活性 | Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation. |
| 体外研究 |
XmAb20717 has binding avidity and contributes to T cell activation, including IL-2, CD45+ cells, and IFNγ. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 |
XmAb20717 (every two days, for 16 d; NSG mice engrafted with KG1a-luc followed by engraftment with huPBMCs) enhances allogeneic anti-tumor responses in mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 |
XmAb20717 (every two days, for 16 d; NSG mice engrafted with KG1a-luc followed by engraftment with huPBMCs) enhances allogeneic anti-tumor responses in mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 性状 | Liquid |
| 溶解性数据 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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