Glyco-Obeticholic acid,98.0%
产品编号:Bellancom-135400| CAS NO:863239-60-5| 分子式:C28H47NO5| 分子量:477.68
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Glyco-Obeticholic acid
产品介绍 | Glyco-obeticholic acid 是牛磺酸的活性代谢物。Obeticholic Acid 是一种口服生物可利用的法尼样X受体 (FXR) 激动剂。 | ||||||||||||
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生物活性 | Glyco-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist. | ||||||||||||
体外研究 |
Obeticholic acid is conjugated with glycine in the liver to form glycol-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate glyco-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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体内研究 | |||||||||||||
性状 | Solid | ||||||||||||
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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参考文献 |