ARQ 621,99.0%
产品编号：Bellancom-16062| CAS NO：1095253-39-6| 分子式：C28H24Cl2FN5O2| 分子量：552.43
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ARQ 621
| 产品介绍 | ARQ 621 是一种变构的有效的选择性 Eg5 抑制剂，Eg5 是一种参与细胞分裂的基于微管的 ATPase 运动蛋白。ARQ 621 具有抗肿瘤活性。ARQ 621 是一种驱动蛋白 (kinesin) 抑制剂。 |
|---|---|
| 生物活性 | ARQ 621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Anti-tumor activity. ARQ 621 is a kinesin inhibitor. |
| 体外研究 |
Over-expression of Eg5 causes genomic instability and tumor formation in mice; therefore, Eg5 is a potential anti-cancer target. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 | |
| 体内研究 | |
| 性状 | Solid |
| 溶解性数据 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| 参考文献 |
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