PGS-IN-1 KME-4,99.51%
产品编号:Bellancom-101587| CAS NO:102271-49-8| 分子式:C19H26O3| 分子量:302.41
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PGS-IN-1 KME-4
产品介绍 | PGS-IN-1是有效的前列腺素合成酶 (prostaglandin synthetase) 抑制剂,IC50 值为0.28 μM;也可抑制5-脂肪氧合酶 (5-lipoxygenase) 的活性,IC50 值为 1.05 μM。 | ||||||||||||
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生物活性 | PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC50 of 0.28 μM; also inhibits 5-lipoxygenase with an IC50 of 1.05 μM. | ||||||||||||
体外研究 |
The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC50=0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC50=1.05 μM). 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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体内研究 | |||||||||||||
性状 | Solid | ||||||||||||
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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