N-Acetyl-Calicheamicin N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin|cas:108212-76-6|西域试剂

N-Acetyl-Calicheamicin N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin,98.0%

产品编号：Bellancom-19791| CAS NO：108212-76-6| 分子式：C₅₇H₇₆IN₃O₂₂S₄| 分子量：1410.39

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-19791		￥19500.00	杭州北京（现货）
Bellancom-19791		￥65000.00	杭州北京（现货）

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N-Acetyl-Calicheamicin N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin

产品介绍

N-Acetyl-Calicheamicin是一类高活性抗肿瘤的抗生素。

生物活性

N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: Antibacterial N-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.

体外研究

体内研究

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (70.90 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.7090 mL	3.5451 mL	7.0902 mL
5 mM	0.1418 mL	0.7090 mL	1.4180 mL
10 mM	0.0709 mL	0.3545 mL	0.7090 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献