ODN 2336|cas:332956-64-6|西域试剂

ODN 2336,90.74%

产品编号：Bellancom-150742| CAS NO：332956-64-6| 分子量：6761.70

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-150742		￥4000.00	杭州北京（现货）
Bellancom-150742		￥12000.00	杭州北京（现货）

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ODN 2336

产品介绍

ODN 2336 是 A 类 CpG ODN（寡脱氧核苷酸），是一种有效的 TLR9 激动剂。ODN 2336 诱导 IFN-α 的产生。ODN 2336 上调 IP-10 mRNA 和 IL-18 mRNA的表达。ODN 2336 可用作疫苗的佐剂。

生物活性

ODN 2336 is a A-Class CpG ODN (oligodeoxynucleotides), is a potent TLR9 agonist. ODN 2336 induces the production of IFN-α. ODN 2336 up-regulates the expression of IP-10 mRNA and IL-18 mRNA. ODN 2336 can be used as adjuvant of vaccines.

体外研究

ODN 2336 (0.5 µM; 24, 48 h) up-regulates the expression of f CD69 and IFN-α.
ODN 2336 (3 µg/ml; 4 h) stimulates strang transcription of IP-10 mRNA after 4 h in human PBMC.
ODN 2336 (3 µg/ml; 2, 4, 16 h) up-regulates the expression of IL-18 mRNA at the 16 htime point.
ODN 2336 (50 μg/mL; 20 h) with IL-3 (10 ng/mL) induces the production of IFN-α in the plasma of adult and cord blood.
ODN 2336 (0.3125-5 µg/ml; 24 h) increases the production of FNA1 in a dose-dependent manner in human PBMCs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

H₂O : 20 mg/mL (2.96 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.1479 mL	0.7395 mL	1.4789 mL
5 mM	---	---	---
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献