KY-556 N556|cas:110816-78-9|西域试剂

KY-556 N556,98.59%

产品编号：Bellancom-U00148| CAS NO：110816-78-9| 分子式：C₃₃H₃₈Cl₂N₂O₁₂| 分子量：725.57

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-U00148	￥1500.00	杭州北京（现货）
Bellancom-U00148	￥2500.00	杭州北京（现货）
Bellancom-U00148	￥5500.00	杭州北京（现货）
Bellancom-U00148	￥9500.00	杭州北京（现货）
Bellancom-U00148	￥15000.00	杭州北京（现货）

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KY-556 N556

产品介绍

KY-556 是一种针对过敏性疾病的具有口服活性的色甘酸二钠 (DSCG) 的前体。

生物活性

KY-556 is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases.

体外研究

体内研究

The oral anti-allergic effect of KY-556 (N-556) is investigated. N-556 (10-100 mg/kg, p.o.) inhibits dose-dependently the 48-hr homologous passive cutaneous anaphylaxis (PCA) in rats, and the duration of action is longer than that of intravenous Disodium cromoglycate (DSCG). N-556 (20 and 100 mg/kg once a day for 20 consecutive days, p.o.) tends to inhibit the histamine release from actively sensitized rat lung fragments. N-556 (100 mg/kg, p.o.) shows the prolongation of survival time in the rat systemic anaphylaxis. N-556 (100 mg/kg, p.o.) significantly inhibits the increased airway resistance in experimental asthma in rats.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 83.33 mg/mL (114.85 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.3782 mL	6.8911 mL	13.7823 mL
5 mM	0.2756 mL	1.3782 mL	2.7565 mL
10 mM	0.1378 mL	0.6891 mL	1.3782 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献