Enrofloxacin monohydrochloride 恩诺沙星单盐酸盐; BAY Vp 2674 monohydrochloride; PD160788 monohydrochloride|cas:93106-59-3|西域试剂

Enrofloxacin monohydrochloride 恩诺沙星单盐酸盐; BAY Vp 2674 monohydrochloride; PD160788 monohydrochloride,99.53%

产品编号：Bellancom-B0502A| CAS NO：93106-59-3| 分子式：C₁₉H₂₃ClFN₃O₃| 分子量：395.86

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货号	价格	库存与货期
Bellancom-B0502A	￥400.00	杭州北京（现货）
Bellancom-B0502A	￥558.00	杭州北京（现货）
Bellancom-B0502A	￥1004.00	杭州北京（现货）

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Enrofloxacin monohydrochloride 恩诺沙星单盐酸盐; BAY Vp 2674 monohydrochloride; PD160788 monohydrochloride

产品介绍

Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) 是一种有效的抗生素，作用于 Mycoplasma bovis，MIC₉₀ 为 0.312 μg/ mL。Enrofloxacin monohydrochloride 具有抗牛痘病毒的活性。

生物活性

Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC₉₀ of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).

体外研究

Mycoplasma bovis is a worldwide pathogen, causative agent of pneumonia, mastitis, arthritis, and a variety of other symptoms in cattle. The antibiotic susceptibility profiles of the Hungarian strains are consistent within the tested group of fluoroquinolones. Three isolates (MYC44, MYC45 and MYC46) have high MIC values (≥10 μg/mL) to Enrofloxacin, while the rest of the strains are inhibited by Enrofloxacin with MICs ≤0.312 or 0.625 μg/mL.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Mice (n=80) undergo transient middle cerebral artery occlusion (MCAo) with reperfusion after 60 minutes. After MCAo, animals are randomly assigned to receive either a daily preventive medication (n=26, Enrofloxacin) starting at the day of MCAo or a therapeutic medication (n=25; Enrofloxacin) after diagnosis of lung infection. Standard treatment started immediately after the appearance of clinical signs (general health score>6) usually between day 4 and 6 after stroke. Both, preventive and standard antibiotic treatment using Enrofloxacin improve survival in a similar way compared with placebo treatment.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

H₂O : 7.14 mg/mL (18.04 mM; Need ultrasonic)

DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.5261 mL	12.6307 mL	25.2615 mL
5 mM	0.5052 mL	2.5261 mL	5.0523 mL
10 mM	0.2526 mL	1.2631 mL	2.5261 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献