Fosmidomycin sodium salt FR-31564,99.18%
产品编号:Bellancom-112853| CAS NO:66508-37-0| 分子式:C4H9NNaO5P| 分子量:205.08
Fosmidomycin sodium salt 是一种磷酸抗生素和抗疟疾药,对革兰氏阴性菌和革兰氏阳性菌均有活性。
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Fosmidomycin sodium salt FR-31564
产品介绍 | Fosmidomycin sodium salt 是一种磷酸抗生素和抗疟疾剂,对革兰氏阴性菌和革兰氏阳性菌均有活性。 | ||||||||||||||||
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生物活性 | Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria. | ||||||||||||||||
体外研究 |
Fosmidomycin sodium salt is a phosphonic acid antibiotic, which is active against both Gram-negative and Gram-positive bacteria. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 |
Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 |
Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
性状 | Solid | ||||||||||||||||
溶解性数据 |
In Vitro:
H2O : 25 mg/mL (121.90 mM; ultrasonic and warming and heat to 60°C) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在 西域 网站选购。
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
参考文献 |
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海关编码 | 2931900090 |
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~39% ![]() 66508-37-0 |
文献:Suresh, Surisetti; Shyamraj, Dharavath; Larhed, Mats Tetrahedron, 2013 , vol. 69, # 3 p. 1183 - 1188 |
~% ![]() 66508-37-0 |
文献:US6680308 B1, ; Page column 15, 16 ; |
~95% ![]() 66508-37-0 |
文献:Yazawa, Hisatoyo; Goto, Shunsuke Tetrahedron Letters, 1985 , vol. 26, # 31 p. 3703 - 3706 |
~68% ![]() 66508-37-0 |
文献:Hemmi; Takeno; Hashimoto; Kamiya Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 111 - 118 |
~% ![]() 66508-37-0 |
文献:Suresh, Surisetti; Shyamraj, Dharavath; Larhed, Mats Tetrahedron, 2013 , vol. 69, # 3 p. 1183 - 1188 |
~% ![]() 66508-37-0 |
文献:US4206156 A1, ; |
上游产品 5 | |
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下游产品 0 |

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