Fosmidomycin sodium salt FR-31564,99.18%

产品编号:Bellancom-112853| CAS NO:66508-37-0| 分子式:C4H9NNaO5P| 分子量:205.08

Fosmidomycin sodium salt 是一种磷酸抗生素和抗疟疾药,对革兰氏阴性菌和革兰氏阳性菌均有活性。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用,

货号 包装 价格 库存与货期 购买量 操作
Bellancom-112853
1400.00 杭州 北京(现货)
Bellancom-112853
2500.00 杭州 北京(现货)
Bellancom-112853
5500.00 杭州 北京(现货)
Bellancom-112853
8800.00 杭州 北京(现货)
Bellancom-112853
12800.00 杭州 北京(现货)

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Fosmidomycin sodium salt FR-31564

产品介绍 Fosmidomycin sodium salt 是一种磷酸抗生素和抗疟疾剂,对革兰氏阴性菌和革兰氏阳性菌均有活性。
生物活性

Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria.

体外研究

Fosmidomycin sodium salt is a phosphonic acid antibiotic, which is active against both Gram-negative and Gram-positive bacteria.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状Solid
溶解性数据
In Vitro: 

H2O : 25 mg/mL (121.90 mM; ultrasonic and warming and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.8761 mL 24.3807 mL 48.7615 mL
5 mM 0.9752 mL 4.8761 mL 9.7523 mL
10 mM 0.4876 mL 2.4381 mL 4.8761 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: PBS

    Solubility: 100 mg/mL (487.61 mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在 西域 网站选购。
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

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