Tremelimumab Ticilimumab; CP-675206|cas:745013-59-6|西域试剂

Tremelimumab Ticilimumab; CP-675206,99.50%

产品编号：Bellancom-P9918| CAS NO：745013-59-6| 分子式：| 分子量：

Tremelimumab（Ticlimumab）是一种对细胞毒性T淋巴细胞抗原-4（CTLA-4）具有特异性的完全人源化单克隆抗体，可用于转移性黑色素瘤研究。

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货号	价格	库存与货期
Bellancom-P9918	￥1900.00	杭州北京（现货）
Bellancom-P9918	￥5700.00	杭州北京（现货）
Bellancom-P9918	￥8500.00	杭州北京（现货）

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产品介绍	Tremelimumab (Ticilimumab) 是一种完全人源化的单克隆抗体，对细胞毒性 T 淋巴细胞抗原 4 (CTLA-4) 具有特异性，可用于转移性黑色素瘤研究。
生物活性	Tremelimumab (Ticilimumab) is a fully humanized monoclonal antibody specific for cytotoxic T-lymphocyte antigen-4 (CTLA-4) and can be used for metastatic melanoma research.
体外研究	Tremelimumab (Ticilimumab) has a higher affinity for CTLA-4-Ig than for CD28-Ig and that the antibody is specific for cynomolgus monkeys and humans. Tremelimumab does not bind to human leukocyte FcγR and does not trigger the release of cytokines avoiding the cytokine release syndrome, but increases the IL-2 production upon stimulation with the staphylococcal enterotoxin A in a concentration-dependent manner. Tremelimumab enhances the IL-2 production in T-cells. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
体内研究
性状	Liquid
溶解性数据
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	. Comin-Anduix B, et al. Tremelimumab: research and clinical development. Onco Targets Ther. 2016 Mar 23;9:1767-76. [Content Brief]

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