Naphthoquine phosphate 磷酸萘酚喹,98.0%
产品编号：Bellancom-17036| CAS NO：173531-58-3| 分子式：C24H34ClN3O9P2| 分子量：605.94
Naphthoquine磷酸盐是抗疟疾化合物。
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Naphthoquine phosphate 磷酸萘酚喹
| 产品介绍 | Naphthoquine phosphate 是一种有效的具有口服活性的抗疟剂。Naphthoquine phosphate 对多种疟原虫的裂殖体具有彻底的杀灭功能，包括恶性疟原虫对氯喹的抗性。 | ||||||||||||||||
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| 生物活性 | Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine. | ||||||||||||||||
| 体外研究 | |||||||||||||||||
| 体内研究 |
The monkeys (Treated with Plasmodium knowlesi) are treated i.g. once daily for 3 days with 6 or 10 mg/kg of Naphthoquine phosphate respectively. At 24 h after Naphthoquine phosphate administration, the parasite reduction rate is higher than 90%. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
| 体内研究 |
The monkeys (Treated with Plasmodium knowlesi) are treated i.g. once daily for 3 days with 6 or 10 mg/kg of Naphthoquine phosphate respectively. At 24 h after Naphthoquine phosphate administration, the parasite reduction rate is higher than 90%. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
| 性状 | Solid | ||||||||||||||||
| 溶解性数据 |
In Vitro:
H2O : 3.33 mg/mL (5.50 mM; Need ultrasonic) DMSO : 1 mg/mL (1.65 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 | ||||||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| 储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
| 参考文献 |
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