Squalamine lactate MSI-1256F|cas:320725-47-1|西域试剂

Squalamine lactate MSI-1256F,98.27%

产品编号：Bellancom-16467| CAS NO：320725-47-1| 分子式：C₃₇H₇₁N₃O₈S| 分子量：718.04

Squalamine lactate 是一种从角鲨体内分到的氨基甾醇，具有抗菌活性，同时可用于新生血管性年龄相关性黄斑变性的研究。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-16467	￥4500.00	杭州北京（现货）
Bellancom-16467	￥8800.00	杭州北京（现货）
Bellancom-16467	￥14000.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

Squalamine lactate MSI-1256F

产品介绍

Squalamine lactate 是一种从角鲨体内分到的氨基甾醇，具有抗菌活性，同时可用于新生血管性年龄相关性黄斑变性的研究。

生物活性

Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.

体外研究

Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Squalamine is ineffective when administered intravitreally and therefore requires intravenous dosing. However, systemic dosing has yielded promising results in rats as well as humans.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Squalamine is ineffective when administered intravitreally and therefore requires intravenous dosing. However, systemic dosing has yielded promising results in rats as well as humans.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : ≥ 36.66 mg/mL (51.06 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.3927 mL	6.9634 mL	13.9268 mL
5 mM	0.2785 mL	1.3927 mL	2.7854 mL
10 mM	0.1393 mL	0.6963 mL	1.3927 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

. Hussain RM, et al. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration. Expert Opin Emerg Drugs. 2017 Sep;22(3):235-246. [Content Brief]

. Emerson MV, et al. Current and emerging therapies for the treatment of age-related macular degeneration. Clin Ophthalmol. 2008 Jun;2(2):377-88. [Content Brief]

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

产品编号(Item Number)

批号(Lot Number)

Squalamine lactate MSI-1256F,98.27%

Squalamine lactate MSI-1256F

化学品安全说明书(MSDS)

质检证书(COA)

在线咨询